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RAID 10, also known as RAID 1+0, is best described as a "stripe of mirrors." This configuration combines the benefits of both mirroring and striping to provide enhanced redundancy and performance. In RAID 10, data is first mirrored between pairs of drives, ensuring redundancy. This means that if one drive fails within a mirrored pair, the system can continue to operate using the other drive.

After this mirroring, the data is striped across these pairs, which improves access speeds as data is read from or written to multiple drives simultaneously. This arrangement provides the fault tolerance of mirroring alongside the performance benefits of striping.

Other options describe different RAID configurations: mirroring without parity refers to a standard RAID 1 setup, spanning across drives does not imply either mirroring or striping but instead indicates a method of combining capacity of multiple drives, and block-level striping with parity is characteristic of RAID 5 or RAID 6, which uses parity information to provide fault tolerance but does not involve the mirroring that RAID 10 relies upon.